Profacgen Enhanced Its PEGylation Services for Biopharmaceutical Industry
Shirley, NY , July 19, 2016 (Newswire.com) - Profacgen, a stat-of-the-art protein service provider based in Long Island, NY, USA, recently enhanced its PEGylation Services for Biopharmaceutical Industry, aiming to help more researchers overcome pharmacological and physicochemical challenges.
Pegylation, the process of attaching polyethylene glycol (PEG) polymer chains to target molecules to monitor their physiochemical properties, can significantly improve the pharmacological and physicochemical properties of peptide and protein therapeutics and reduce side effects. PEGylated proteins show great advantage over non-PEGylated proteins in terms of non-toxicity, low immunogenicity, high solubility and mobility in solution. And protein PEGylation can also mask the target protein drugs from the host’s immune system.
“For its established therapeutic value and high flexibility, PEGylation is regarded as a valuable tool in efficient drug development. We newly developed a series of technologies that increase the site-specificity of our PEGylation process. We do believe with our enhanced services, we can help the biopharmaceutical industry to maintain forward process of promising drug candidates.” commented Crystal, the chief marketing staff in Profacgen.
According to its official speaker, this optimized service carries a few new features including: Highly site-specific modifications, Improved target solubility and stability, Reduced immunogenicity and toxicity, Enhanced protection from proteolytic degradation and Increased in vivo efficacy and clinical effectiveness.
Profacgen provides process development and cGMP manufacturing services for biological active ingredients. We have ready access to state-of-the-art biopharmaceutical product development and manufacturing facilities and our staff scientists have demonstrable expertise in all aspects of biopharmaceutical manufacturing, from facility design and operation to the ability to provide best advice relating to product development. We also save our clients a great deal of time with bioprocess scale-up services. Our fermentation laboratories are equipped with state-of-the-art fermentors and bioreactors that enable us to express protein in large scale. Our customers can choose to enter into the protein expression pipeline at any stage depending on their needs.
Mailing Address: 45-1 Ramsey Road, Shirley, NY 11967, USA