Drug-Drug Interactions: Understanding Proposed FDA Regulatory Updates and Applying In Vitro and Physiologically Based Techniques

Xtalks Life Science Webinars

As the population ages, approximately 33 percent of patients are considered polypharmacy, taking multiple drugs at the same time (Bjerrum, Gonzalez Lopez-Valcarcel et al. 2008). The percentage of the population taking at least five different medications increases from 25 percent to 46 percent as the population ages from age 65 to 79 (Charlesworth, Smit et al. 2015). Based on these statistics, it is not a surprise that many patients have experienced a problem with how drugs or other substances (like coffee) interact in their body.

It’s the responsibility of drug developers to understand how a potential new substance will interact with other drugs.

Join industry experts Dan Albaugh, Senior Manager, Global Drug Metabolism, and Joshua Fohey, Senior Manager, Global PK/PD Modeling and Simulation at Covance, for a live webinar on Monday, Dec. 17, 2018, at 11 a.m. EST (4 p.m. GMT).

In this webinar, featured speakers will:

  • Review the proposed changes to the FDA regulatory guidance to ensure that the appropriate data are being captured in a drug development program
  • Explore what else can be done with data to better understand enzymes, transporters and drug disposition
  • Present case studies demonstrating the use of PBPK models to simulate potential exposure changes of both the victim and perpetrator compounds and discuss how these results can be used in regulatory conversations and how they can help in the design of additional experiments to optimize a program

For more information or to register for this event, visit Drug-Drug Interactions: Understanding Proposed FDA Regulatory Updates and Applying In Vitro and Physiologically Based Techniques.

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Contact:

Sarah Hand
​Tel: +1 (416) 977-6555 ext 224
​Email: shand@xtalks.com

Source: Xtalks


Categories: Pharmaceuticals and Biotech

Tags: Covance, Drug Discovery and Development, Drug Safety, Drug-Drug Interactions, FDA Guidance, Life Sciences, PBPK, Pharmaceutical, Pharmaceutical Regulation, PK/PD, Xtalks


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Xtalks is a leading provider of educational webinars to the global life science, food and medical device community.