Aronora Announces Clinical Data to Be Presented at the 62nd American Society of Hematology Annual Meeting

Presentation to include clinical data from Aronora's phase 2 study of AB023, a factor XI-targeted antibody that is being developed for the treatment and prevention of thrombosis and inflammation.

Aronora Inc., a clinical stage biotechnology company developing innovative therapies for hematologic diseases, today announced that clinical data from its completed phase 2 study of AB023 will be presented at the 62nd American Society of Hematology (ASH) Annual Meeting, taking place virtually Dec. 5-8, 2020. 

Details of the oral presentation are as follows:

Title: Safety and Efficacy of the Contact Activation Inhibitor AB023 in Patients with End-Stage Renal Disease on Chronic Hemodialysis: A Phase 2, Double-Blind, Randomized, Placebo-Controlled Trial

Publication Number: 237

Session: 332. Anticoagulation and Antithrombotic Therapy: Novel Agents, Reversal Drugs and Indications 

Session Date: Saturday, Dec. 5, 2020 

Session Time: 2:00 p.m. - 3:30 p.m.

Presentation Time: 2:15 p.m.

Abstracts are available via the ASH meeting website at https://www.hematology.org/meetings/annual-meeting/abstracts

AB023 is a recombinant antibody that targets coagulation factor XI (FXI) and specifically inhibits FXI activation by factor XII without blocking its activation by thrombin. This phase 2 study evaluated the safety and efficacy of AB023 in patients with end stage renal disease on chronic hemodialysis. Additional information about the trial can be found at https://clinicaltrials.gov/ct2/show/NCT03612856

Preclinical and early clinical development has been partially supported by the National Heart, Lung, and Blood Institute and National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIH) under award numbers R44HL106919, R44HL128016, and R44AI088937. This content is solely the responsibility of Aronora and does not necessarily represent the official views of the NIH.

For more information, please visit www.aronorabio.com.

Media Contact: 
Erik Tucker 
Phone: (503) 530-6842
Email: erik.tucker@aronorabio.com

Source: Aronora, Inc

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Categories: Pharmaceuticals and Biotech

Tags: AB023, antithrombotic, aronora, biotech, blood clot, clinical trial, factor XI, factor XII, hemodialysis, xisomab