Brittany Barreto, Ph.D.

Brittany Barreto, Ph.D.

Raleigh, North Carolina, United States
19K followers 500+ connections

Join to follow

About

Every day Dr. Barreto dedicates her work to advancing women’s health by equipping…

Activity

Experience

  • Imperial College London Graphic

    Imperial College London

  • -

    Raleigh, North Carolina, United States

  • -

    Washington DC-Baltimore Area

  • -

    Raleigh, North Carolina, United States

  • -

  • -

  • -

  • -

  • -

    Houston, Texas Area

  • -

    Houston, Texas Area

  • -

    Houston, Texas Area

  • -

    Houston, Texas

  • -

  • -

  • -

    Madison, NJ

Education

  • Baylor College of Medicine Graphic

    Baylor College of Medicine

    -

    Activities and Societies: Graduate student council

    Trained as an expert in Molecular and Human Genetics.
    Able to design and execute experiments to solve knowledge gaps in the literature.

  • -

    Activities and Societies: Francophone Association, Project Yaakaar, A.S.i.A. Club, Rotex

    Received an excellent liberal arts education where I became a well rounded student and learned to articulate my arguments and findings through writing and oral presentations.

Licenses & Certifications

  • Life Science Entrepreneurship

    -

    Issued

  • Flow Cytometry

    -

    Issued

Volunteer Experience

  • Volunteer

    Eleventh Hour Rescue

    - 2 years 4 months

    Animal Welfare

    Animal shelter- I walked dogs and cleaned crates. I helped adopt out and foster the dogs that needed homes.

  • Chairman Of The Board

    Cooper's Crossroad

    - 1 year 1 month

    Health

    ​The mission of Cooper's Crossroad is to raise awareness of the profound and insidious effects of trauma by offering seminars, workshops, lectures, and retreats to those interested in becoming educated on its impact and available cutting edge treatment. We are a non-profit organization set upon 100 pristine acres of farmland, surrounded by nature's beauty, including horses, cows, dogs, and mountain views.

Publications

  • The Small RNA GcvB promotes Mutagenic Break Repair by Opposing the Membrane Stress Response

    Journal of Bacteriology

    Microbes and human cells possess mechanisms of mutagenesis activated by stress responses. Stress-inducible mutagenesis mechanisms may provide important models for mutagenesis that drives host-pathogen interactions, antibiotic resistance, and possibly much of evolution generally. In Escherichia coli, repair of DNA double-strand breaks is switched to a mutagenic mode, using error-prone DNA polymerases, via the SOS DNA-damage and the general (σS) stress responses. We investigated small RNA (sRNA)…

    Microbes and human cells possess mechanisms of mutagenesis activated by stress responses. Stress-inducible mutagenesis mechanisms may provide important models for mutagenesis that drives host-pathogen interactions, antibiotic resistance, and possibly much of evolution generally. In Escherichia coli, repair of DNA double-strand breaks is switched to a mutagenic mode, using error-prone DNA polymerases, via the SOS DNA-damage and the general (σS) stress responses. We investigated small RNA (sRNA) clients of RNA chaperone Hfq, which promotes mutagenic break repair (MBR), and found that GcvB promotes MBR by allowing a robust σS response, achieved via opposing the membrane stress (σE) response. First, cells that lack gcvB were MBR-deficient in two standard assays. Second, ∆gcvB cells displayed reduced σS-dependent transcription in colony and flow-cytometric assays, but not reduced σS-protein levels. Third, the σS-dependent-transcription and MBR defects of ∆gcvB cells were alleviated by deletion of rssB, which increases σS levels. These data imply that GcvB promotes mutagenesis by allowing a normal σS response. Fourth, ∆gcvB cells were highly induced for the σE response. Moreover, their high σE response underlies their reduced MBR, in that a special σE-response-blocking mutation restored mutagenesis to ∆gcvB cells. We suggest that GcvB may promote the σS response and mutagenesis indirectly, by promoting membrane integrity, which keeps σE levels lower. At high levels, σE might inhibit σS-dependent transcription by titrating RNA polymerase, to which σS would normally bind, so that σS may be unable to regulate transcription at the normal level. The data show the delicate balance of stress-response modulation of mutagenesis.

    Other authors

  • Double-Strand-Break Repair, Mutagenesis and Stress. In Stress and Environmental Control of Gene Expression in Bacteria

    Wiley-Blackwell Publishers

    Other authors
    • Elizabeth Rogers
    • Maria Bravo Nunez
    • Philip Minnick
    • Diana Vera Cruz
    • Philip Hastings
    • Susan Rosenberg

Courses

  • Project Management

    -

  • R

    -

Honors & Awards

  • HYPE Impact Award; Startup SuperStar

    Greater Houston Partnership

    The HYPE Impact Awards are presented to outstanding young leaders who strive for excellence and have achieved innovative, business-savvy and ground-breaking ideas.

  • Top 100 Young Executives in America

    Business Journals

    Produced by The Business Journals, this first-of-its-kind list spotlights 100 younger executives who already are having an impact on business being done in communities across the nation.

    And, because they’re still early in their careers, these are executives who could be shaping how business gets done for years to come.

    These executives were identified in conjunction with editors and staff writers across The Business Journals’ network of more than 40 publications. The list draws…

    Produced by The Business Journals, this first-of-its-kind list spotlights 100 younger executives who already are having an impact on business being done in communities across the nation.

    And, because they’re still early in their careers, these are executives who could be shaping how business gets done for years to come.

    These executives were identified in conjunction with editors and staff writers across The Business Journals’ network of more than 40 publications. The list draws in large part from those publications’ respective Forty Under 40 productions over the past year. From that mass of well more than 1,000 executives who’ve been profiled locally over the past 12 months, the field was narrowed to spotlight the 100 executives you see here.

  • Women Who Mean Business; Woman to Watch

    Houston Business Journal

    Criteria for selection includes career achievement, contribution to company, community involvement and leadership.

  • Houston Business Journal 40 Under 40

    Houston Business Journal

    Winners are chosen by a panel of judges not affiliated with the HBJ. Candidates are evaluated based on professional accomplishments, philanthropic efforts, and other exemplary qualities. The winners are Houston's top 40 businessmen and women in the city of Houston under 40 years of age.

  • 8-Stranded Beta Barrel Jelly Roll Graduate Student Teacher Award 2015-2016

    BCM Graduate Student Council

    Chosen by students for the best teacher assistance for the entire 2015-2016 academic year at Baylor College of Medicine. I taught bacterial and phage genetics to 200 first year PhD students.

  • Bravo Award

    Department of Molecular and Human Genetics

    Recognized as best graduate student teacher at BCM

  • Phi Beta Kappa

    Drew University

    Nation's oldest and most prestigious academic honors society.

  • Dorothy R. Baldwin Scholarship

    Drew University

    Offered to a woman of high academic record who shows outstanding leadership

  • Sidney Udenfriend Prize

    Drew University

    Awarded to a student who demonstrates exceptional promise for fundamental and applied research

  • Featured in Drew Today

    Drew University

    Highlighted for my work on novel molecules that reactivate mutant p53

    http://www.drew.edu/news/2012/08/03/a-novel-idea

  • Future of Microbiologist

    American Society for Microbiology

Languages

  • English

    -

  • French

    -

Organizations

  • American Society for Microbiology

    Founder of Texas Medical Center ASM student/post-doc chapter

    - Present

Recommendations received

10 people have recommended Brittany

Join now to view

View Brittany’s full profile

  • See who you know in common
  • Get introduced
  • Contact Brittany directly
Join to view full profile

People also viewed

Explore collaborative articles

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.

Explore More

Add new skills with these courses

See all courses