Deciphering the Password of Cancer Cells Helps to Kill Them

Scientists found that deciphering the password of cancer cells could be helpful in killing these cells and then improve health condition.

After years of effort, scientists have deciphered the genetic code of a variety of cancers, including the entire genetic code of lung cancer, skin cancer and breast cancer; this study is likely to bring a new revolution for the treatment of varying cancers. The researchers said that if people could develop a new drug directed against gene mutation, then future cancer treatment could realize symptomatic medication.

Actually, many projects of cancer treatment have been carried out for many years such as the Cancer Genome Anatomy Project (CGAP), which aims at producing necessary information and technology tools for decoding the molecular structure of tumor cells like Chimeric CPPs. More specifically, relevant data about cancer cells have already been noted. For example, some reports indicated that cell genome of lung cancer contains 23,000 mutant genes while skin cancer (malignant melanoma) genome contains 33,000 mutant genes. Generally, most mutant genes are harmless, and they can become part of the genome. However, some mutant genes will pull the trigger, bringing unexpected cancers. 

As is known, all types of cancers take the gene coding errors as an incentive, because external stimulation may cause genetic mutations and then produce a gene coding error. This is the reason that make cells grow at a wrong place and time in a wrong way, thereby such cells would become cancer cells. When it comes to genome of breast cancer, scientists found these genomes contain many different types of deoxyribonucleic acid (DNA) defects through comparing 24 genomes of breast tumors. Each DNA defect reflects the characteristics of certain cancer subspecies. Whereas, current research is not comprehensive yet, which means more efforts are required such as research on argireline

In recent days, researchers have reported a new method using magnetic nanodiscs to kill the cancer cells. They developed a thin nickel-iron magnetic alloy disc, in which all the atoms are arranged in concentric circles, forming a magnetic turbulence. When another interactive magnetic field acts on its magnetic field, the oscillation occurs. Researchers also noted such oscillation would damage membrane of cancer cells and start the programmed cell death when in laboratory tests. Clearly, the method is used in magnetic field, which is equivalent to the amount of 1/10 of the previous methods. In addition, the frequency is also very low so that it’s possible to avoid side effects associated with high-intensity magnetic field.

This method solves the previous limit of magnetic nanoparticles in clinical treatment, such as the accumulation of high magnetic field and permanent magnetic particles in the body, which are obstacles to prevent magnetic nanoparticles treatment in clinical applications. In brief, these cancer genome projects and cancer treatment researches are an important cornerstone of future cancer medicines. 


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