MDI with corticosteroids control respiratory disease by suppressing overactive immune response in the lungs which can cause inflammation.
May 5, 2014 (Newswire.com) - Inhaled corticosteroids are the most effective treatment for asthma. Several types of inhalers help treat asthma and include metered-dose inhalers, metered-dose inhalers with a spacer, and dry powder inhalers. Nebulizers are also used for the treatment of asthma, but are for patients who have trouble using inhalers, such as infants and children. These devices contain chemicals - corticosteroids or glucocorticosteroids - that help prevent and treat inflammation of the airways.
Corticosteroids help control asthma and this can allow the patient to engage in activities they were not able to before, improving their overall quality of life. Corticosteroids won't cure asthma, but they are a very effective treatment for relief of symptoms and prevention of asthma attacks.Corticosteroids contribute to the reduction of symptoms long-term if taken every day (Partners Healthcare Asthma Center, 2012). Side effects of long-term use may include slight delay in growth (Mayo Clinic Staff, 2012). When an asthma attack occurs, the airways of the lungs become inflamed and increase the production of mucus. When irritants (both environmental and non-environmental) enter the lungs, the body's immune response is to generate to produce chemicals that cause inflammation.
These chemicals mediate more immunity cells to the area, which contribute to even more inflammation and mucus production. Corticosteroids work by reducing inflammation in the lungs and suppressing the immunity cells that release the chemicals responsible for inflammation (Beltina Encyclopedia of Health). By suppressing the immunity cells, chemicals that cause inflammation - histamine and leukotriene - are no longer produced and other immunity cells are not recruited to the airways.
MDI with corticosteroids control respiratory disease by suppressing overactive immune response in the lungs which can cause inflammation. Lung Inflammation constricts airways and irritates the lungs, leading to spasms in the smooth muscles lining the lungs. MDIs are available in various brand names such as Flovent, Azmacort, Beclovent, Vanceril, Budesonide, Qvar and Aerobid.